Disease Models & Mechanisms (DMM) is an Open Access biomedical research journal focusing on the use of model systems to better understand, diagnose and treat human disease.
The primary aim of DMM is to promote human health by inspiring collaboration between basic and clinical researchers in translational science. The journal is committed to presenting rigorously peer-reviewed research that has significant translational impact. The interdisciplinary nature of DMM means that a diverse range of diseases, approaches and models fall within its broad scope. DMM is guided by an international team of expert research-active Editors, led by Editor-in-Chief Elizabeth Patton and Deputy Editor-in-Chief Elaine Mardis, and supported by an outstanding Editorial Advisory Board.
Due to COVID-19, DMM staff are working remotely, but our editorial operations continue to run as usual. Please contact us by email at firstname.lastname@example.org if you have any queries. Thank you for your patience and understanding.
For more information on measures DMM is taking to support the community at this time, please see here.
Call for papers – The RAS pathway
Our upcoming special issue is welcoming submissions until 3 May 2021. Guest-edited by Donita Brady (Perelman School of Medicine at the University of Pennsylvania, USA) and Arvin Dar (Icahn School of Medicine at Mount Sinai, USA), the issue will focus on the targeting the RAS pathway.
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News from DMM
In her first Editorial as Editor-in-Chief, Liz Patton sets out her vision and priorities for DMM, focusing on four thematic challenges: mechanisms of disease, innovative technologies, disease progression through time and therapy.
DMM has welcomed two new Editors to the team: Editor Rickie Patani and Associate Editor Monkol Lek.
A collaboration between the Development and Disease Models & Mechanisms journal teams, this virtual Meeting will unite developmental biologists, human geneticists and clinical researchers to focus on building bridges from bench to clinic. Register your interest and find out more.
In this month’s Editor’s Choice, Hay Dvir and colleagues describe how high-dose vitamin B1 can protect overnourished sheep from developing hepatic stearosis and could be an effective treatment for fatty liver disease in humans.
Learn more about this paper in our First Person interview with Mugagga Kalyesubula and Ramgopal Mopuri, the co-first authors of this study.
A new Review by Citra Mattar and team summarises in vivo, in vitro and in silico models of congenital heart disease and how they can be integrated to facilitate the discovery of new treatments.
Also in this issue, Catherine Abbott and colleagues review mouse models of epilepsy.